The process by which the cell identifies and repairs the damages done to the DNA molecules is known as DNA repair. DNA damage can be caused due to normal metabolic activities or environmental factors like Radiations or Ultra-Violet light. This results in the molecular lesions as many as 1 million per day. There is a high possibility that the lesions cause structural damage to the DNA molecule and they can also modify or eliminate totally the ability of cell to transcribe the gene that affected the encodes of DNA.
Several other lesions are harmful for the mutation of the genome of cell and this affects the survival of its daughter cell after undergoing the process of mitosis. The process of DNA repair is carried out constantly as it responds continuously to the damage in structure of DNA.
Extra cellular environment, age of cell, type of cell are some of the factors on which rate of DNA repair is dependent. Any cell which has a large amount of DNA damage or it can no longer be effectively repaired, such cell enter the following 3 stages
Several other lesions are harmful for the mutation of the genome of cell and this affects the survival of its daughter cell after undergoing the process of mitosis. The process of DNA repair is carried out constantly as it responds continuously to the damage in structure of DNA.
Extra cellular environment, age of cell, type of cell are some of the factors on which rate of DNA repair is dependent. Any cell which has a large amount of DNA damage or it can no longer be effectively repaired, such cell enter the following 3 stages
- Senescence, which is stage of dormancy and it is irreversible
- programmed cell death, apoptosis which is also known as cell suside
- unregulated division of cell which finally leads to serious health problems like cancer and tumor
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