Gene therapy

Genes are carried on the chromosomes and they are the basic functional and physical units of hereditary. Genes provide the guidance for specific sequences of the basis which encodes instructions of making proteins. Even thought gene get vital attention the key role is played by the proteins, which perform most of the life functions and is also responsible for number of cellular structures. But in case if the genes are altered, proteins cannot perform their normal functions and may result in genetic disorders.

Gene therapy provides various ways and means for fixing the genetic disorders or defects. There are number of approaches which can be used by Gene therapy. Depending upon the type of disorder the most suitable approach is adopted generally. Following are some of the common approaches adopted by the research teams:

An insertion of the normal gene is done in the non specific location within genome to replace the non functional gene.

The normal gene can be replaced in place of some abnormal gene via the homologous recombination

With the help of reverse mutation, the abnormal or the defective gene can be repaired by which it can return to its normal gene functions.

There can be modification done in the regulation of the particular gene.